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ALKBH1 Monoclonal Antibody (OTI4C4), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA805636

Encompass_Preferred

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Catalog No. 50-168-0786


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Description

Description

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
Specifications

Specifications

ALKBH1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q13686
ALKBH1
Human recombit protein fragment corresponding to amino acids 1-245 of human ALKBH1 produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin)
OTI4C4
Unconjugated
ALKBH1
ABH, ABH1, ALKBH, alkB, hABH
Mouse
Affinity Chromatography
RUO
8846
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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