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ALKBH1 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735795 Shop All Proteintech Group Inc Products
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50-173-5795 150 μL
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Catalog No. 50-173-5795 Supplier Proteintech Group Inc Supplier No. 279731AP150UL
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Description

Rabbit Polyclonal Antibody

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.

Specifications

Antigen ALKBH1
Applications Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ALKBH1
Gene Accession No. Q13686
Gene Alias ABH, ABH1, alkB, ALKBH, ALKBH1, DNA lyase ABH1, hABH
Gene Symbols ALKBH1
Host Species Rabbit
Immunogen ALKBH1 Fusion Protein Ag27520
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8846
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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