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Invitrogen™ ALKBH3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5100786
Description
Antibody detects endogenous levels of total ALKBH3.
Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
Specifications
ALKBH3 | |
Polyclonal | |
Unconjugated | |
Alkbh3 | |
1700108H04Rik; 1810020C19Rik; Abh3; AlkB homolog 3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); Alkbh3; Alkylated DNA repair protein alkB homolog 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC 1; DEPC1; DEPC-1; FLJ43614; hABH3; m MGC118790; mABH3; MGC118792; MGC118793; MGC134125; PCA1; Prostate cancer antigen 1; prostate cancer antigen-1; RP23-375N21.4 | |
Rabbit | |
Affinity chromatography | |
RUO | |
221120, 362169, 69113 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q5XIC8, Q8K1E6, Q96Q83 | |
Alkbh3 | |
A synthesized peptide derived from human ALKBH3(Accession Q96Q83), corresponding to amino acid residues R164-T214. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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