Invitrogen™ ALKBH3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100786

Catalog No. PIPA5100786

Description

Antibody detects endogenous levels of total ALKBH3.

Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.

Specifications

• Antigen: ALKBH3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Alkbh3
• Gene Alias: 1700108H04Rik; 1810020C19Rik; Abh3; AlkB homolog 3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); Alkbh3; Alkylated DNA repair protein alkB homolog 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC 1; DEPC1; DEPC-1; FLJ43614; hABH3; m MGC118790; mABH3; MGC118792; MGC118793; MGC134125; PCA1; Prostate cancer antigen 1; prostate cancer antigen-1; RP23-375N21.4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221120, 362169, 69113
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5XIC8, Q8K1E6, Q96Q83
• Gene Symbols: Alkbh3
• Immunogen: A synthesized peptide derived from human ALKBH3(Accession Q96Q83), corresponding to amino acid residues R164-T214.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov