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Invitrogen™ ALKBH3 Polyclonal Antibody
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Catalog No. PIPA565438
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100 μL
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PIPA565438 100 μL
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Catalog No. PIPA565438 Supplier Invitrogen™ Supplier No. PA565438
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NPHWHPVLRTL KNRIEENTGH TFNSLLCNLY RNEKDSVDWH SDDEPSLGRC PIIASLSFGA TRTFEMRKKP PPEENGDYTY VERVKIPLDH GTLLIMEGAT QADWQHRVPK EY Highest antigen sequence identity to the following orthologs - mouse 93%, rat 94%.

Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALKBH3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Alkbh3
Gene Accession No. Q96Q83
Gene Alias 1700108H04Rik; 1810020C19Rik; Abh3; AlkB homolog 3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); Alkbh3; Alkylated DNA repair protein alkB homolog 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC 1; DEPC1; DEPC-1; FLJ43614; hABH3; m MGC118790; mABH3; MGC118792; MGC118793; MGC134125; PCA1; Prostate cancer antigen 1; prostate cancer antigen-1; RP23-375N21.4
Gene Symbols Alkbh3
Host Species Rabbit
Immunogen Recombinant Human ALKBH3. Recombinant protein control fragment (Product #RP-106116).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221120
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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