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Invitrogen™ ALKBH4 Polyclonal Antibody
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Catalog No. PIPA5113466
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100 μg
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Catalog No. Quantity
PIPA5113466 100 μg
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Catalog No. PIPA5113466 Supplier Invitrogen™ Supplier No. PA5113466
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Description

Rabbit Polyclonal Antibody

ALKBH4 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes (PubMed:23673617). Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration (PubMed:23673617). In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALKBH4
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene ALKBH4
Gene Accession No. Q9D8F1, Q9NXW9
Gene Alias 2010004B12Rik; ABH4; Abj4; alkB homolog 4, lysine demethylase; alkB homolog 4, lysine demthylase; alkB, alkylation repair homolog 4; alkB, alkylation repair homolog 4 (E. coli); Alkbh4; Alkylated DNA repair protein alkB homolog 4; alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; DNA N6-methyl adenine demethylase ALKBH4; Lysine-specific demethylase ALKBH4; probable alpha-ketoglutarate-dependent dioxygenase ABH4; RGD1308608
Gene Symbols ALKBH4
Host Species Rabbit
Immunogen Recombinant Human Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 protein (1-115AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54784, 72041
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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