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  6. Invitrogen™ ALKBH5 Recombinant Rabbit Monoclonal Antibody (2S4Q6)

Invitrogen™ ALKBH5 Recombinant Rabbit Monoclonal Antibody (2S4Q6)
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Catalog No. FEMA551412
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100 μL
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FEMA551412 100 μL
MA568753 20 μL
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Catalog No. FEMA551412 Supplier Invitrogen™ Supplier No. MA551412
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: PERSDYEEQQ LQKEEEARKV KSGIRQMRLF SQDECAKIEA RIDEVVSRAE KGLYNEHTVD RAPLRNKYFF GEGYTYGAQL QKRGPGQERL YPPGDVDEIP EWVHQLVIQK LVEHRVIPEG FVNSAVINDY QPGGCIVSHV DPIHIFERPI VSVSFFSDSA LCFGCKFQFK PIRVSEPVLS LPVRRGSVTV LSGYAADEIT HCIRPQDIKE RRAVIILRKT RLDAPRLETK SLSSSVLPPS YASDRLSGNN RDPALKPKRS HRKADPDAAH RPRILEMDKE ENRRSVLLPT HRRRGSFSSE NYWRKSYESS EDCSEAAGSP ARKVKMRRH.

ALKBH5 (RNA demehtylase ALKBH5) is a dioxygenase that demethylates RNA by oxidative demethylation. Specifically, it demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Demethylation of m6A mRNA affects mRNA processing and export. ALKBH5 can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro). It requires molecular oxygen, alpha-ketoglutarate and iron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALKBH5
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 2S4Q6
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene ALKBH5
Gene Accession No. D3ZKD3, Q3TSG4, Q6P6C2
Gene Alias ABH5; AlkB family member 5, RNA demethylase; alkB homolog 5, RNA demethylase; alkB, alkylation repair homolog 5; alkB, alkylation repair homolog 5 (E. coli); Alkbh5; Alkylated DNA repair protein alkB homolog 5; alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; AW050020; AW215868; E130207K11; OFOXD; OFOXD1; oxoglutarate and iron-dependent oxygenase domain containing; probable alpha-ketoglutarate-dependent dioxygenase ABH5; RGD1309496; RNA demethylase ALKBH5
Gene Symbols ALKBH5
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 268420, 303193, 54890
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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