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Invitrogen™ ALKBH7 Polyclonal Antibody
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Catalog No. PIPA558842
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100 μL
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PIPA558842 100 μL
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Catalog No. PIPA558842 Supplier Invitrogen™ Supplier No. PA558842
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SGPSVLSRLQ DAAVVRPGFL STAEEETLSR ELEPELRRRR YEYDHWDAAI HGFRETEKSR WSEASRAILQ RV Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.

ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221 amino acid protein belonging to the alkB family. ALKBH7 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. ALKBH7 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognizedfor having the greatest gene density of the human chromosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALKBH7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ALKBH7
Gene Accession No. Q9BT30
Gene Alias 2310045B01Rik; 2510008E23Rik; Abh7; alkB homolog 7; alkB, alkylation repair homolog 7; alkB, alkylation repair homolog 7 (E. coli); Alkbh7; Alkylated DNA repair protein alkB homolog 7; alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial; probable alpha-ketoglutarate-dependent dioxygenase ABH7; SPATA11; spermatogenesis associated 11; spermatogenesis cell proliferation related protein; spermatogenesis cell proliferation-related protein; Spermatogenesis-associated protein 11; UNQ6002; UNQ6002/PRO34564
Gene Symbols ALKBH7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ALKBH7. Recombinant protein control fragment (Product #RP-102874).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84266
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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