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ALKBH7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501730253 Shop All Proteintech Group Inc Products
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50-173-0253 150 μL
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Catalog No. 50-173-0253 Supplier Proteintech Group Inc Supplier No. 154701AP150UL
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Description

Rabbit Polyclonal Antibody

ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221 amino acid protein belonging to the alkB family. ALKBH7 is one of many homologs of the Escherichia coli protein AlkB. AlkB functions to protect DNA and RNA against damage from environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate and molecular oxygen as the oxidizing agent. ALKBH7 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognizedfor having the greatest gene density of the human chromosomes.

Specifications

Antigen ALKBH7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ALKBH7
Gene Accession No. Q9BT30
Gene Alias ABH7, ALKBH7, SPATA11, UNQ6002
Gene Symbols Alkbh7
Host Species Rabbit
Immunogen ALKBH7 Fusion Protein Ag7772
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66400, 679944, 84266
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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