Invitrogen™ ALOX5 Monoclonal Antibody (OTI3F1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526829

Catalog No. PIMA526829

Description

ALOX5 Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: ALOX5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09917
• Gene Symbols: ALOX5
• Immunogen: Human recombinant protein fragment corresponding to amino acids 18-364 of ALOX5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3F1
• Conjugate: Unconjugated
• Gene: ALOX5
• Gene Alias: 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 240
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid