Invitrogen™ ALOX5 Recombinant Rabbit Monoclonal Antibody (5C5Z2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538050

Catalog No. PIMA538050

Description

Positive Samples: Raji, Rat lung Immunogen sequence: CYRWITGDVE VVLRDGRAKL ARDDQIHILK QHRRKELETR QKQYRWMEWN PGFPLSIDAK CHKDLPRDIQ FDSEKGVDFV LNYSKAMENL FINRFMHMFQ S.

This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.

Specifications

• Antigen: ALOX5
• Classification: Recombinant Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09917, P12527, P48999
• Gene Symbols: ALOX5
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ALOX5 (P09917).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5C5Z2
• Conjugate: Unconjugated
• Gene: ALOX5
• Gene Alias: 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11689, 240, 25290
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid