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Invitrogen™ ALOXE3 Polyclonal Antibody
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Catalog No. PIPA585063
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100 μL
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PIPA585063 100 μL
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Catalog No. PIPA585063 Supplier Invitrogen™ Supplier No. PA585063
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YQWIEGYCTV ELRPGTARTI CQDSLPLLLD HRTRELRARQ ECYRWKIYAP GFPCMVDVNS FQEMESDKKF ALTKTTTCVD QGDSS Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 86%.

This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALOXE3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ALOXE3
Gene Accession No. Q9BYJ1
Gene Alias ALOXE3; arachidonate lipoxygenase 3; ARCI3; E-LOX; eLOX3; e-LOX-3; eLOX-3; epidermal lipoxygenase; epidermal LOX-3; Epidermis-type lipoxygenase 3; hydroperoxide isomerase ALOXE3; Hydroperoxy icosatetraenoate dehydratase
Gene Symbols ALOXE3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ALOXE3. Recombinant protein control fragment (Product #RP-93476).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 59344
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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