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Invitrogen™ ALP Monoclonal Antibody (4D11)

Description
4D11 reacts with CRASH, a 308 AA glycoprotein, sharing 32% homology with human asparaginase and identical to Asparaginase-Like Protein (ALP) found in rat sperm. CRASH is found in a variety of tumors but only occasionally in normal tissues. Especially ovarian cancers are highly positive. CRASH is further found in brain tumors, some colonic cancers, some lung cancers, some prostate cancers, uterine cancers, some breast cancers and some thyroid cancers. It was not found in serum. In Western blot 3 bands are demonstrated of 45 kDa, 28 kDa and 15 kDa.
Specifications
Specifications
| Antigen | ALP |
| Applications | ELISA, Immunohistochemistry (Frozen), Western Blot |
| Classification | Monoclonal |
| Clone | 4D11 |
| Concentration | 100 μg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | Asrgl1 |
| Gene Accession No. | Q7L266 |
| Gene Alias | 2410004D18Rik; ALP; ALP1; asparaginase and isoaspartyl peptidase 1; asparaginase like 1; asparaginase-like 1; asparaginase-like 1 protein; asparaginase-like protein 1; Asparaginase-like sperm autoantigen; ASRGL1; AU040643; AW060375; Beta-aspartyl-peptidase; CRASH; FLJ22316; Glial asparaginase; Gliap; Hiob; Hiob2; isoaspartyl dipeptidase; Isoaspartyl peptidase/L-asparaginase; Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain; L-asparaginase; L-asparagine amidohydrolase; testis secretory sperm-binding protein Li 242mP; zgc:103568 |
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