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Invitrogen™ ASZ1 Polyclonal Antibody
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Catalog No. PIPA554234
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100 μL
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PIPA554234 100 μL
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Catalog No. PIPA554234 Supplier Invitrogen™ Supplier No. PA554234
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGHTQVVALL VAHGAEVNTQ DENGYTALTW AARQGHKNIV LKLLELGANK MLQTKDGKMP SEIAKRNKHH EIFNLLSFTL NPLEGKLQQL TKED Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ASZ1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Asz1
Gene Accession No. Q8WWH4
Gene Alias 4933400N19Rik; ALP1; ANKL1; ankyrin repeat, SAM and basic leucine zipper domain containing 1; ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; ankyrin-like 1; ankyrin-like protein 1; Asz1; C7orf7; CT1.19; GASZ; germ cell-specific ankyrin, SAM and basic leucine zipper domain containing protein; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein; Orf3
Gene Symbols Asz1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ALP1. Recombinant protein control fragment (Product #RP-92763).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 136991
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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