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Invitrogen™ alpha-1b Adrenergic Receptor Monoclonal Antibody (471802)
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Catalog No. PIMA524191
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100 μg
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Catalog No. Quantity
PIMA524191 100 μg
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Catalog No. PIMA524191 Supplier Invitrogen™ Supplier No. MA524191
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Description

Mouse Monoclonal Antibody

This antibody stains human ADRA1B transfectants but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS.

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
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Specifications

Antigen alpha-1b Adrenergic Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone 471802
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Adra1b
Gene Accession No. P35368
Gene Alias [a]1b; ADA1B; ADRA1; ADRA1B; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor; adrenoceptor alpha 1B; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; alpha1B-adrenergic receptor; ALPHA1BAR
Gene Symbols Adra1b
Host Species Mouse
Immunogen NS0 mouse myeloma cell line transfected with human ADRA1B Met1-Phe520.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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