Invitrogen™ alpha-1b Adrenergic Receptor Monoclonal Antibody (471802)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524191

Catalog No. PIMA524191

Description

This antibody stains human ADRA1B transfectants but not irrelevant transfectants. Reconstitute at 0.5 mg/mL in sterile PBS.

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

Specifications

• Antigen: alpha-1b Adrenergic Receptor
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P35368
• Gene Symbols: Adra1b
• Immunogen: NS0 mouse myeloma cell line transfected with human ADRA1B Met1-Phe520.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry
• Clone: 471802
• Conjugate: Unconjugated
• Gene: Adra1b
• Gene Alias: [a]1b; ADA1B; ADRA1; ADRA1B; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor; adrenoceptor alpha 1B; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; alpha1B-adrenergic receptor; ALPHA1BAR
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 147
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized