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Invitrogen™ alpha-1b Adrenergic Receptor Polyclonal Antibody
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Catalog No. PIPA526411
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400 μL
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PIPA526411 400 μL
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Catalog No. PIPA526411 Supplier Invitrogen™ Supplier No. PA526411
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology.

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
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Specifications

Antigen alpha-1b Adrenergic Receptor
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Adra1b
Gene Accession No. P35368
Gene Alias [a]1b; ADA1B; ADRA1; ADRA1B; Adrenergic alpha 1B- receptor; adrenergic receptor, alpha 1b; adrenergic, alpha-1B-, receptor; adrenoceptor alpha 1B; alpha 1B-adrenoceptor; alpha 1B-adrenoreceptor; alpha-1B adrenergic receptor; Alpha-1B adrenoceptor; alpha-1B adrenoreceptor; alpha-1B-adrenergic receptor; alpha1B-adrenergic receptor; ALPHA1BAR
Gene Symbols Adra1b
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 270-297 amino acids from the central region of human ADRA1B.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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