Invitrogen™ alpha-2a Adrenergic Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120835

Catalog No. PIPA5120835

Description

Positive test controls include: K-562, Mouse brain, Mouse Spinal cord. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein. Immunogen sequence: RRTRVPPSRR GPDAVAAPPG GTERRPNGLG PERSAGPGGA EAEPLPTQLN GAPGEPAPAG PRDTDALDLE ESSSSDHAER PPGPRRPERG PRGKGKARAS QVKPGDSLPR RGPGATGIGT PAAGPGEERV GAAKASRWRG R.

Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.

Specifications

• Antigen: alpha-2a Adrenergic Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Adra2a
• Gene Alias: ADRA2; Adra-2; ADRA2A; Adra-2a; ADRA2R; ADRAR; adrenergic receptor, alpha 2a; adrenergic, alpha-2A-, receptor; adrenoceptor alpha 2A; alpha(2A)AR; alpha-2 adrenergic receptor subtype C10; alpha2A; alpha-2A adrenergic receptor; Alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha2A-adrenergic receptor; ALPHA2AAR; alpha-2AAR; alpha2A-AR; alpha-2AAR subtype C10; alpha-2-adrenergic receptor, platelet type; alpha2-C10; alpha-2D adrenergic receptor; AW122659; CA2-47; OTTHUMP00000058849; RATRG20; RG20; subtype alpha2-C10; ZNF32
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11551, 150, 25083
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P08913, P22909, Q01338
• Gene Symbols: Adra2a
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2A (NP_000672.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG