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Invitrogen™ alpha-2a Adrenergic Receptor Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA1048
Description
PA1-048 detects alpha-2A adrenergic receptor (A2AAR) from human, rat and mouse tissues. PA1-048 has been successfully used in Western blot and immunohistochemistry procedures. By Western blot, this antibody detects an ~45 kDa protein representing A2AAR from mouse kidney membrane preparations. The PA1-048 immunogen is a synthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR. This sequence is completely conserved between human, mouse, rat, and porcine A2AAR.
Alpha-2-adrenergic receptors (ADRA2A) are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. ADRA2A mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G protein. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system.
Specifications
alpha-2a Adrenergic Receptor | |
Polyclonal | |
Unconjugated | |
Adra2a | |
ADRA2; Adra-2; ADRA2A; Adra-2a; ADRA2R; ADRAR; adrenergic receptor, alpha 2a; adrenergic, alpha-2A-, receptor; adrenoceptor alpha 2A; alpha(2A)AR; alpha-2 adrenergic receptor subtype C10; alpha2A; alpha-2A adrenergic receptor; Alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha2A-adrenergic receptor; ALPHA2AAR; alpha-2AAR; alpha2A-AR; alpha-2AAR subtype C10; alpha-2-adrenergic receptor, platelet type; alpha2-C10; alpha-2D adrenergic receptor; AW122659; CA2-47; OTTHUMP00000058849; RATRG20; RG20; subtype alpha2-C10; ZNF32 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
11551, 150, 25083 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.6 mg/mL | |
PBS with 1 mg/mL BSA and 0.05% sodium azide | |
P08913, P22909, Q01338 | |
Adra2a | |
Synthetic peptide corressponding to residues R(218) I Y Q I A K R R T R V P P S R R G(235) of the 3rd intracellular loop of human A2AAR. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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