Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. APP4518

Invitrogen™ alpha-2c Adrenergic Receptor Polyclonal Antibody
GREENER_CHOICE

Catalog No. APP4518
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
APP4518 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. APP4518 Supplier Invitrogen™ Supplier No. PA14518
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

PA1-4518 detects alpha-2c AR in human, rat, and mouse samples. PA1-4518 has been successfully used in Western blot and Immunohistochemistry procedures. The PA1-4518 immunogen is a synthetic peptide corresponding to internal residues of the alpha-2c Adrenergic Receptor. Maintain at 4ºC for 3 months or at -20ºC for longer periods. Avoid repeated freeze-thaw cycles.

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha-2c Adrenergic Receptor
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ADRA2C
Gene Accession No. P18825, P22086, Q01337
Gene Alias [a]2C; Adra 2c; ADRA2C; Adra-2c; ADRA2L2; ADRA2RL2; ADRARL2; Adrenergic alpha2C- receptor class I; adrenergic receptor, alpha 2c; adrenergic, alpha-2C-, receptor; Adrenergic, alpha2C-, receptor class I; adrenoceptor alpha 2C; Alpha 2CAR; alpha-2 adrenergic receptor subtype C4; alpha2 AR C4; alpha2 C4; alpha2-AR-C4; alpha2C; Alpha-2C adrenergic receptor; alpha-2C adrenoceptor; Alpha-2C adrenoreceptor; alpha2-C4; alpha-2C-adrenergic receptor; ALPHA2CAR; alpha-2CAR; Alpha-2C-AR; subtype alpha2-C4
Gene Symbols ADRA2C
Host Species Rabbit
Immunogen Synthetic peptide corresponding to internal residues of the alpha-2c Adrenergic Receptor.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11553, 152, 24175
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.