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Invitrogen™ alpha Actinin 2/3 Polyclonal Antibody
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Catalog No. PIPA5106486
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PIPA5106486 100 μL
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Catalog No. PIPA5106486 Supplier Invitrogen™ Supplier No. PA5106486
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Actinin alpha 2/3.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha Actinin 2/3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ACTN2
Gene Accession No. O88990, P35609, Q08043, Q9JI91
Gene Alias 1110008F24Rik; actinin alpha 2; actinin alpha 3; actinin alpha 3 (gene/pseudogene); Actinin alpha3; actinin, alpha 2; actinin, alpha 3; Actinin-alpha3; ACTN2; ACTN3; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 3; Alpha-actinin-2; alpha-Actinin3; alpha-actinin-3; alphaActinin-3; CMD1AA; CMH23; F-actin cross-linking protein
Gene Symbols ACTN2, ACTN3
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACTN2(Accession P35609), corresponding to amino acid residues K38-D88.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11472, 11474, 171009, 291245, 88, 89
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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