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alpha-actinin (Actinin alpha 1) Mouse anti-Human, Clone: OTI7A4, liquid, TrueMAB™
SDP

Catalog No. 501671382
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30 μL
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50-167-1382 30 μL
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Catalog No. 50-167-1382 Supplier OriGene Supplier No. TA500072S
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Description

Mouse Monoclonal Antibody

Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen alpha-actinin (Actinin alpha 1)
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI7A4
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ACTN1
Gene Accession No. P12814
Gene Alias BDPLT15
Gene Symbols ACTN1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 650-893 of human alpha-actinin produced in E.coli.
Purification Method Affinity Chromatography
Quantity 30 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 87
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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