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alpha-actinin (Actinin alpha 1) Mouse anti-Human, Clone: OTI7A4, liquid, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene TA500072

Description
Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.Specifications
alpha-actinin (Actinin alpha 1) | |
Monoclonal | |
Unconjugated | |
ACTN1 | |
BDPLT15 | |
Mouse | |
Affinity Chromatography | |
RUO | |
87 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI7A4 | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P12814 | |
ACTN1 | |
Human recombit protein fragment corresponding to amino acids 650-893 of human alpha-actinin produced in E.coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2a |
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