Invitrogen™ alpha Actinin Monoclonal Antibody (A1G2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA536095

Catalog No. PIMA536095

Description

alpha Actinin Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: alpha Actinin
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P12814, Q7TPR4, Q9Z1P2
• Gene Symbols: ACTN1
• Immunogen: Recombinant protein within Human ACTN1 aa 388-619.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: A1G2
• Conjugate: Unconjugated
• Gene: ACTN1
• Gene Alias: 3110023F10Rik; actinin; actinin 1 smooth muscle; actinin alpha 1; actinin, alpha 1; Actn1; Actn1a; alpha actinin 1a; alpha-actinin; alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F-actin cross-linking protein; fibroblast alpha actinin; FLJ40884; FLJ54432; hypothetical protein; hypothetical protein LOC524770; I79_004057; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 109711, 81634, 87
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid