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Invitrogen™ alpha Adducin Polyclonal Antibody
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Catalog No. PIPA527460
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100 μL
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Catalog No. Quantity
PIPA527460 100 μL
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Catalog No. PIPA527460 Supplier Invitrogen™ Supplier No. PA527460
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurakt, Raji. Predicted reactivity: Mouse (95%), Rat (96%), Zebrafish (89%), Xenopus laevis (90%), Chicken (92%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha Adducin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene ADD1
Gene Accession No. P35611, Q9QYC0
Gene Alias Add1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; erythrocyte adducin subunit alpha
Gene Symbols ADD1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11518, 118
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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