Invitrogen™ alpha Adducin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580317

Catalog No. PIPA580317

Description

This antibody has specificity for Human ADD1/adducin 1.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Specifications

• Antigen: alpha Adducin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADD1
• Gene Alias: Add1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; erythrocyte adducin subunit alpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 118
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: P35611
• Gene Symbols: ADD1
• Immunogen: A synthetic peptide corresponding to the center region of the Human ADD1/adducin 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG