Invitrogen™ alpha Catenin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529247

Catalog No. PIPA529247

Description

Recommended positive controls: A431, HeLa, HepG2, mouse brain, Rat2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.

Specifications

• Antigen: alpha Catenin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTNNA2
• Gene Alias: 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI481747; AI988031; alpha E catenin; alpha E-catenin; Alpha N-catenin; alpha(E)-catenin; alpha(N)-catenin; alpha-catenin; alpha-catenin-related protein; alpha-E-catenin; alphaE-catenin; alpha-N-catenin; alphaN-catenin; cadherin associated protein; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; CAP102; CAPR; CAP-R; catenin; catenin (cadherin associated protein), alpha 1; catenin (cadherin associated protein), alpha 2; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; catenin alpha 1; catenin alpha 2; Catenin alpha1; catenin alpha-1; Catenin alpha2; Catenin alpha-2; catenin, alpha 1; Catenin-alpha1; Catenin-alpha2; Catna; Catna1; Catna2; cdf; cerebellar deficient folia; chp; CT114; CTNNA1; Ctnna2; CTNR; FLJ36832; FLJ52416; HGNC:2509; MDPT2; Neural alpha-catenin; NY-REN-13 antigen; renal carcinoma antigen NY-REN-13
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12385, 12386, 1495, 1496, 297357, 307505
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P26231, P26232, P35221, Q61301
• Gene Symbols: CTNNA1, CTNNA2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 40 and 324 of Human alpha Catenin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG