Invitrogen™ alpha Galactosidase Monoclonal Antibody (2H7G10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA529309

Catalog No. PIMA529309

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human alpha-Galactosidase A/GLA.

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Specifications

• Antigen: alpha Galactosidase
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P06280
• Gene Symbols: GLA
• Immunogen: Recombinant Human alpha-Galactosidase A/GLA protein (Met1-Leu429).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA
• Clone: 2H7G10
• Conjugate: Unconjugated
• Gene: GLA
• Gene Alias: Agalsidase; agalsidase alfa; Ags; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase; alpha-D-galactoside galactohydrolase 1; alpha-gal A; alpha-galactosidase A; GALA; galactosidase alpha; galactosidase, alpha; GLA; Melibiase
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2717
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid