Invitrogen™ alpha-II Spectrin Recombinant Rabbit Monoclonal Antibody (JU32-09)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532826

Catalog No. PIMA532826

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: alpha-II Spectrin
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P16086, P16546, Q13813
• Gene Symbols: SPTAN1
• Immunogen: Synthetic peptide within Human Alpha Fodrin aa 46-95.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: JU32-09
• Conjugate: Unconjugated
• Gene: SPTAN1
• Gene Alias: (ALPHA)II-SPECTRIN; 2610027H02Rik; A2a; a--fodrin; alpha; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain; brain alpha-spectrin; EIEE5; FLJ44613; Fodrin alpha chain; inhibitory protein factor; IPF; NEAS; noerythroid alpha-spectrin 2; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; nonerythroid alpha-spectrin; nonerythroid alpha-spectrin 2; putative alpha-spectrin; SPECA; Spectrin; Spectrin alpha; spectrin alpha chain; Spectrin alpha chain brain; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1 (alpha-fodrin); spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; Spna2; Spna-2; Spta2; Sptan1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20740, 64159, 6709
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid