Invitrogen™ alpha N-Catenin Monoclonal Antibody (T.44.7)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514963

Catalog No. PIMA514963

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other -alpha-catenin family members.

The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.

Specifications

• Antigen: alpha N-Catenin
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CTNNA2
• Gene Alias: AI481747; alpha N-catenin; alpha(N)-catenin; alpha-catenin-related protein; alpha-N-catenin; cadherin associated protein; cadherin-associated protein, related; cancer/testis antigen 114; CAPR; CAP-R; catenin (cadherin associated protein), alpha 2; catenin (cadherin-associated protein), alpha 2; catenin alpha 2; catenin alpha-2; Catna; Catna2; cdf; cerebellar deficient folia; chp; CT114; CTNNA2; CTNR; DKFZp686H02198; OTTHUMP00000216460; OTTHUMP00000216462
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12386, 1496, 297357
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: T.44.7
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P26232, Q61301
• Gene Symbols: CTNNA2
• Immunogen: Synthetic peptide corresponding to the carboxy-terminal sequence of human a-N-Catenin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG