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Invitrogen™ Alpha Sarcoglycan Polyclonal Antibody
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Catalog No. PIPA552450
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100 μL
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PIPA552450 100 μL
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Catalog No. PIPA552450 Supplier Invitrogen™ Supplier No. PA552450
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SALDRGGRVP LPIEGRKEGV YIKVGSASPF STCLKMVASP DSHARCAQGQ PPLLSCYDTL APHFRVDWCN VTLVDKSVPE PADEVPTPGD GILEHDPFFC PPTEAPDRDF LVD Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.

The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Alpha Sarcoglycan
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SGCA
Gene Accession No. Q16586
Gene Alias 50 kDa dystrophin-associated glycoprotein; 50DAG; 50kD DAG; adhalin; ADL; Alpha-sarcoglycan; alpha-SG; Asg; DAG2; DMDA2; Dystroglycan 2; Dystroglycan2; dystroglycan-2; LGMD2D; limb girdle muscular dystrophy 2D; sarcoglycan alpha; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); sarcoglycan, alpha (dystrophin-associated glycoprotein); SCARMD1; SG alpha; SG-alpha; Sgca
Gene Symbols SGCA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SGCA. Recombinant protein control fragment (Product #RP-90085).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6442
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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