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Invitrogen™ alpha Synuclein Recombinant Rabbit Monoclonal Antibody (HL1242)
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Catalog No. FEMA550306
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100 μL
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FEMA550306 100 μL
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Catalog No. FEMA550306 Supplier Invitrogen™ Supplier No. MA550306
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Description

Rabbit Recombinant Monoclonal Antibody

alpha Synuclein Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (F), IHC (P)

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha Synuclein
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL1242
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene SNCA
Gene Accession No. O55042, P37377, P37840
Gene Alias Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)
Gene Symbols SNCA
Host Species Rabbit
Immunogen Full length human alpha Synuclein Recombinant protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20617, 29219, 6622
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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