alpha Tubulin Monoclonal Antibody (TU-01), Alexa Fluor™ 555, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA138000A555

Catalog No. PIMA13800AZ

Description

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predomitly found in morphologically differentiated neurologic cells.

Specifications

• Antigen: alpha Tubulin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q71U36, P68369
• Gene Symbols: TUBA1A
• Immunogen: Peptide that corresponds to aa 65-79 in the N-terminus of alpha-tubulin
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence
• Clone: TU-01
• Conjugate: Alexa Fluor 555
• Gene: TUBA1A
• Gene Alias: LIS3, Tuba1, TUBA3, Tuba-1, B-ALPHA-1
• Host Species: Mouse
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22142, 7846
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid

For Research Use Only