Invitrogen™ TUBA4A Recombinant Rabbit Monoclonal Antibody (JM73-24)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532738

Catalog No. PIMA532738

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa, are homologous but not identical. The alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

Specifications

• Antigen: TUBA4A
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P68366, P68368, Q5XIF6
• Gene Symbols: TUBA4A
• Immunogen: Synthetic peptide within Human alpha Tubulin 4A aa 399-448.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Clone: JM73-24
• Conjugate: Unconjugated
• Gene: TUBA4A
• Gene Alias: Alpha-tubulin 1; Alpha-tubulin 4; alpha-tubulin isotype M-alpha-4; ALS22; H2-ALPHA; M[a]4; Testis-specific alpha-tubulin; TUBA1; Tuba4; TUBA4A; Tubulin alpha; tubulin alpha 4a; tubulin alpha-1 chain; Tubulin alpha-4 chain; tubulin alpha-4A chain; Tubulin H2-alpha; tubulin, alpha 1 (testis specific); tubulin, alpha 4; tubulin, alpha 4a
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 22145, 316531, 7277
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid