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Invitrogen™ ALPL Monoclonal Antibody (W8B2B10)
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Catalog No. PIMA546185
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100 μg
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PIMA546185 100 μg
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Catalog No. PIMA546185 Supplier Invitrogen™ Supplier No. MA546185
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Description

Mouse Monoclonal Antibody

This antibody recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.

Alkaline phosphatase is a homodimeric protein enzyme (86 kDa), containing two zinc atoms crucial to its catalytic function per monomer, and it is optimally active at alkaline pH environments. The enzyme is found in prokaryotes and eukaryotes, with the same general function but in different structural forms suitable to organism's environment. ALP plays a role in liver metabolism and development within the skeleton. In bacteria, ALP acts as a source of inorganic phosphate. In yeast, ALP can be a useful protein for studying membrane protein sorting.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALPL
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone W8B2B10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene ALPL
Gene Accession No. P05186
Gene Alias Akp2; Akp-2; Alkaline phosphatase 2; alkaline phosphatase 2, liver; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase precursor (EC 3.1.3.2); alkaline phosphatase tissue non-specific isoform; alkaline phosphatase tissue non-specific isoform/TNS-AP; alkaline phosphatase, biomineralization associated; alkaline phosphatase, intestinal; alkaline phosphatase, liver/bone/kidney; alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphomonoesterase; ALPI; Alpl; APTNAP; AP-TNAP; FLJ40094; FLJ93059; glycerophosphatase; HOPS; IAP; intestinal alkaline phosphatase; intestinal-type alkaline phosphatase; Kasahara isozyme; liver/bone/kidney isozyme; liver/bone/kidney-type alkaline phosphatase; MGC161443; MGC167935; PHOA; tissue-nonspecific alkaline phosphatase; tissue-nonspecific alkaline phosphatase precursor; tissue-nonspecific ALP; Tissue-nonspecific ALP alkaline phosphatase; TNAP; TNSALP; TNS-AP
Gene Symbols ALPL
Host Species Mouse
Immunogen WERI-RB-1 retinoblastoma cell line.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100170147, 101123195, 102189447, 249, 403548
Target Species Human, Canine, Monkey, Sheep, Pig, Goat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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