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ALS2CR8 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987925
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50-198-7925 100 μL
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Catalog No. 50-198-7925 Supplier Bioss Supplier No. BS7684R
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Description

Rabbit Polyclonal Antibody

CARF (calcium-response factor), also known as ALS2CR8 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) or NYD-SP24, is a 725 amino acid nuclear protein. Expressed in a wide variety of tissues with highest expression in the hippocampus, CARF is thought to be a transcription factor that associates with the p53 tumor suppression pathway. CARF cooperates, co-localizes and is co-regulated with ARF, an ADP-ribosylation factor, and, through this interaction, helps to mediate ARF-p53-induced apoptotic signaling. This apoptotic pathway is implicated in cell cycle control, proper cellular development, response to DNA damage and the aging process, suggesting that CARF participates in various events throughout the cell.

Specifications

Antigen ALS2CR8
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CARF
Gene Accession No. Q8N187
Gene Alias ALS2CR8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog; calcium response factor; calcium responsive transcription factor; Calcium-response factor; calcium-response factor CaRF; Calcium-responsive transcription factor; Carf; ECBRC-FC1; ECBRC-FC2; NYD-SP24; Testis development protein NYD-SP24
Gene Symbols CARF
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ALS2CR8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79800
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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