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  6. 175710

ALX 5407 hydrochloride, Tocris Bioscience™
GREENER_CHOICE

Catalog No. 175710
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective non-transportable GlyT1 inhibitor

Selective non-transportable inhibitor of the glycine transporter GlyT1 (IC50 values are 3 nM and > 100 μM for human GlyT1c and GlyT2 respectively). Does not recognize other glycine sites, including the glycine site on the NMDA receptor (IC50 > 100 μM).

Racemate also available.

Chemical Identifiers

CAS 200006-08-2
Molecular Formula C24H25ClFNO3
Molecular Weight (g/mol) 429.916
InChI Key RPDGSZCYSJWQEE-GNAFDRTKSA-N
Synonym alx 5407 hydrochloride, n-3r-3-1,1'-biphenyl-4-yloxy-3-4-fluorophenyl propyl-n-methylglycine hydrochloride, 3r-3-1,1'-biphenyl-4-yloxy-3-4-fluorophenyl propyl methyl amino acetic acid hydrochloride, alx-5407 hydrochloride, +-nfps, alx 5407 hydrochloride hplc, n-3r-3-1,1'-biphenyl-4yloxy-3-4-fluorophenyl propyl-n-methylglycine hydrochloride, n-3r-3-1,1'-biphenyl-4-yl oxy-3-4-fluorophenyl propyl-n-methylglycine-hydrogen chloride 1/1
PubChem CID 16078946
IUPAC Name 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid;hydrochloride
SMILES CN(CCC(C1=CC=C(C=C1)F)OC2=CC=C(C=C2)C3=CC=CC=C3)CC(=O)O.Cl

Specifications

Quantity 10 mg
Formula Weight 429.92
Percent Purity >98%
Chemical Name or Material ALX 5407 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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