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Invitrogen™ ALX4 Monoclonal Antibody (KAB4)
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Catalog No. PIMA125326
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50 μg
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PIMA125326 50 μg
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Catalog No. PIMA125326 Supplier Invitrogen™ Supplier No. MA125326
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Mouse Monoclonal Antibody

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALX4
Applications Western Blot
Classification Monoclonal
Clone KAB4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide; pH 7.4
Gene ALX4
Gene Accession No. Q9H161
Gene Alias ALX homeobox 4; ALX4; ALX-4; aristaless 4; Aristaless-like 4; aristaless-like homeobox 4; CRS5; FND2; Homeobox protein aristaless-like 4; homeodomain transcription factor ALX4; KIAA1788; lst; Strong's luxoid
Gene Symbols ALX4
Host Species Mouse
Immunogen Recombinant full length protein (Human).
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60529
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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