Invitrogen™ ALX4 Monoclonal Antibody (OTI1F2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526062

Catalog No. PIMA526062

Description

ALX4 Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

Specifications

• Antigen: ALX4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9H161
• Gene Symbols: ALX4
• Immunogen: Full length human recombinant protein of ALX4 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1F2
• Conjugate: Unconjugated
• Gene: ALX4
• Gene Alias: ALX homeobox 4; ALX4; ALX-4; aristaless 4; Aristaless-like 4; aristaless-like homeobox 4; CRS5; FND2; Homeobox protein aristaless-like 4; homeodomain transcription factor ALX4; KIAA1788; lst; Strong's luxoid
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 60529
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid