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Tocris Bioscience™ AM 580
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Catalog No. 076010
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50 mg
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Catalog No. Quantity
07-601-0 10 mg
07-605-0 50 mg
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Catalog No. 07-601-0 Supplier Tocris Bioscience™ Supplier No. 0760/10
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Description

Retinoic acid analog; RARα agonist

AM 580 is an analog of retinoic acid that acts as a selective RARα agonist (EC50 values are 0.3, 8.6 and 13 nM for RARα, RARβ and RARγ respectively). Significantly induces IL-4, IL-5 and IL-13 and inhibits IL-12 and IFNγ synthesis, and induces cell differentiation with over 7 times the activity of retinoic acid in vitro.

AM 580 synthesized to Ancillary Material Grade also available.

Chemical Identifiers

CAS 102121-60-8
Molecular Formula C22H25NO3

Specifications

Quantity 10 mg
Formula Weight 351.44
Purity >98%
Molecular Weight (g/mol) 351.45
Chemical Name or Material AM 580

Safety and Handling

Recommended Storage Store at Room Temperature
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