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AM2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987902
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100 μL
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50-198-7902 100 μL
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Catalog No. 50-198-7902 Supplier Bioss Supplier No. BS7655R
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Description

Rabbit Polyclonal Antibody

The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.

Specifications

Antigen AM2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene AIFM2
Gene Accession No. Q9BRQ8
Gene Alias 5430437E11Rik; Aifm2; AMID; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; Apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2
Gene Symbols AIFM2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human AMID/AIFM2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84883
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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