AMACR Monoclonal Antibody (OTI2A11), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800813

Catalog No. 50-167-8565

Description

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: AMACR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9UHK6
• Gene Symbols: AMACR
• Immunogen: Full length human recombit protein of human AMACR produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2A11
• Conjugate: Unconjugated
• Gene: AMACR
• Gene Alias: AMACRD, CBAS4, P504S, RACE, RM
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23600
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid