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  5. Tocris Bioscience™ AMD 3100 octahydrochloride

Tocris Bioscience™ AMD 3100 octahydrochloride
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Catalog No. 329910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Highly selective CXCR4 antagonist

Highly selective CXCR4 chemokine receptor antagonist (IC50 values are 0.02 - 0.13 and > 25 μM for CXCR4 and all other chemokine receptors respectively). Switches inflammatory responses from Th2 to Th1 type and reduces airway hyperresponsiveness in a mouse model of asthma. Potently inhibits HIV-1 and HIV-2 replication in vitro (EC50 = 4 - 35 nM) and mobilizes hematopoietic stem cells in vivo. Attenuates cocaine place preference and locomotor stimulation in rats. Attenuates microglial activation neurological function after ischemic stroke in mice.

Chemical Identifiers

CAS 155148-31-5
Molecular Formula C28H62Cl8N8

Specifications

Quantity 10 mg
Formula Weight 794.48
Purity >98%
Molecular Weight (g/mol) 794.46
Chemical Name or Material AMD 3100 octahydrochloride

Safety and Handling

Recommended Storage Desiccate at -20°C
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