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  5. Tocris Bioscience™ AMD 3100 octahydrochloride

Tocris Bioscience™ AMD 3100 octahydrochloride
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Catalog No. 329950
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32-995-0 50 mg
32-991-0 10 mg
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Catalog No. 32-995-0 Supplier Tocris Bioscience™ Supplier No. 3299/50
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Description

Highly selective CXCR4 antagonist

Highly selective CXCR4 chemokine receptor antagonist (IC50 values are 0.02 - 0.13 and > 25 μM for CXCR4 and all other chemokine receptors respectively). Switches inflammatory responses from Th2 to Th1 type and reduces airway hyperresponsiveness in a mouse model of asthma. Potently inhibits HIV-1 and HIV-2 replication in vitro (EC50 = 4 - 35 nM) and mobilizes hematopoietic stem cells in vivo. Attenuates cocaine place preference and locomotor stimulation in rats. Attenuates microglial activation neurological function after ischemic stroke in mice.

Chemical Identifiers

CAS 155148-31-5
Molecular Formula C28H62Cl8N8

Specifications

Quantity 50 mg
Formula Weight 794.48
Purity >98%
Molecular Weight (g/mol) 794.46
Chemical Name or Material AMD 3100 octahydrochloride

Safety and Handling

Recommended Storage Desiccate at -20°C
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