Invitrogen™ AMER2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570111

Catalog No. PIPA570111

Description

This target displays homology in the following species: Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%.

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex.

Specifications

• Antigen: AMER2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AMER2
• Gene Alias: 2600011E07Rik; AMER2; APC membrane recruitment 2; APC membrane recruitment protein 2; Fam123a; family with sequence similarity 123, member A; family with sequence similarity 123A; protein FAM123A; RGD1559605
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 72125
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8CCJ4
• Gene Symbols: AMER2
• Immunogen: synthetic peptide directed towards the middle region of human AMER2 (aa 39-88).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov