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Tocris Bioscience™ AMG 333

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Quantity:
10 mg
50 mg
Description
AMG 333 is a potent and selective TRPM8 antagonist (IC50 values are 13 and 20 nM for hTRPM8 and rTRPM8, respectively). Displays high selectivity over other TRP channels (IC50 >20 μM, TRPV1/V3/V4/A1). Inhibits icilin -induced wet-dog shake in rats and suppresses cold-induced increases in blood pressure in the rat cold-pressor test.
Specifications
Specifications
Quantity | 10 mg |
Molecular Formula | C20H12F5N3O4 |
Formula Weight | 453.33 |
Product Type | Antagonist |
Purity | 98% |
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