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Tocris Bioscience™ AMG 548

Catalog No. 392010
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10 mg
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Catalog No. Quantity
39-201-0 10 mg
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Catalog No. 39-201-0 Supplier Tocris Bioscience™ Supplier No. 3920/10
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Description

Potent and selective p38α inhibitor

Potent and selective inhibitor of p38α (Ki values are 0.5, 3.6, 2600 and 4100 nM for p38α, p38β, p38γ and p38δ respectively). Displays >1000-fold selectivity against 36 other kinases; inhibits whole blood LPS-stimulated TNFα (IC50 = 3 nM). Efficacious in acute and chronic models of arthritis.

Chemical Identifiers

CAS 864249-60-5
Molecular Formula C29H27N5O

Specifications

Quantity 10 mg
Formula Weight 461.56
Purity >98%
Molecular Weight (g/mol) 461.569
Chemical Name or Material AMG 548

Safety and Handling

Recommended Storage Store at -20°C
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