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Invitrogen™ AMID Monoclonal Antibody (3A11)
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Catalog No. PIMA522795
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100 μg
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Catalog No. Quantity
PIMA522795 100 μg
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Catalog No. PIMA522795 Supplier Invitrogen™ Supplier No. MA522795
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Description

Mouse Monoclonal Antibody

Peptide Sequence: VRQEVKEILL RKGVQLLLSE RVSNLEELPL NEYREYIKVQ TDKGTEVATN LVILCTGIKI NSSAYRKAFE SRLASSGALR VNEHLQVEGH SNVYAIGDCA.

The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMID
Applications ELISA, Immunoprecipitation
Classification Monoclonal
Clone 3A11
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene AIFM2
Gene Accession No. Q9BRQ8
Gene Alias 5430437E11Rik; AIFM2; Amid; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2
Gene Symbols AIFM2
Host Species Mouse
Immunogen AIFM2 (NP_116186, 188 a.a. ~ 287 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84883
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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