Invitrogen™ AMID Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111150

Catalog No. PIPA5111150

Description

Immunogen sequence: NLVILCTGIK INSSAYRKAF ESRLASSGAL RVNEHLQVEG HSNVYAIGDC ADVRTPKMAY LAGLHANIAV ANIVNSVKQR PLQAYKPGAL TFLLSMGRND GVGQISGFYV GRLMVRLTKS RDLFVSTSWK TM.

The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.

Specifications

• Antigen: AMID
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AIFM2
• Gene Alias: 5430437E11Rik; AIFM2; Amid; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84883
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BRQ8
• Gene Symbols: AIFM2
• Immunogen: Recombinant Protein corresonding to Human AMID. Recombinant protein control fragment (Product #RP-89960).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov