Invitrogen™ AMID Recombinant Rabbit Monoclonal Antibody (7X9B2)

Catalog No.	Quantity
FEMA551255	100 μL

Catalog No. FEMA551255 Supplier Invitrogen™ Supplier No. MA551255

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: KDSFHHNVAA LRASVETGFA KKTFISYSVT FKDNFRQGLV VGIDLKNQMV LLQGGEALPF SHLILATGST GPFPGKFNEV SSQQAAIQAY EDMVRQVQRS RFIVVVGGGS AGVEMAAEIK TEYPEKEVTL IHSQVALADK ELLPSVRQEV KEILLRKGVQ LLLSERVSNL EELPLNEYRE YIKVQTDKGT EVATNLVILC TGIKINSSAY RKAFESRLAS SGALRVNEHL QVEGHSNVYA IGDCADVRTP KMAYLAGLHA NIAVANIVNS VKQRPLQAYK PGALTFLLSM GRNDGVGQIS GFYVGRLMVR LTKSRDLFVS TSWKTMRQS.

The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.

Specifications

• Antigen: AMID
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: 7X9B2
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene: AIFM2
• Gene Accession No.: Q8BUE4, Q9BRQ8
• Gene Alias: 5430437E11Rik; AIFM2; Amid; apoptosis inducing factor, mitochondria associated 2; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated 2; apoptosis-inducing factor, mitochondrion-associated, 2; apoptosis-inducing factor-like mitchondrion-associated inducer of death; apoptosis-inducing factor-like mitochondrion-associated inducer of death; D730001I10Rik; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; PRG3; RP11-367H5.2
• Gene Symbols: AIFM2
• Host Species: Rabbit
• Immunogen: Recombinant protein (or fragment)
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 361843, 71361, 84883
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Format: Liquid
• Isotype: IgG