Invitrogen™ AMIGO1 Monoclonal Antibody (L86/33)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527611

Catalog No. PIMA527611

Description

1 μg/mL of MA5-27611 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 60-80kDa depending on maturity/glycosylation. This antibody was formerly sold as clone S86-36.

Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. [UniProt].

Specifications

• Antigen: AMIGO1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q80ZD7, Q80ZD8, Q86WK6
• Gene Symbols: Amigo1
• Immunogen: Fusion protein amino acids 394-492 (cytoplasmic C-terminus) of human AMIGO-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Clone: L86/33
• Conjugate: Unconjugated
• Gene: Amigo1
• Gene Alias: adhesion molecule with Ig like domain 1; adhesion molecule with Ig-like domain 1; ali2; alivin 2; alivin-2; AMIGO; AMIGO 1; AMIGO1; AMIGO-1; amigo1 {ECO:0000250; amphoretin-induced gene and ORF; amphoterin induced gene and ORF (Amigo); amphoterin-induced gene and ORF; amphoterin-induced protein 1; KIAA1163; MGC25558; OTTHUMP00000013379; RP23 89M15.6; transmembrane protein AMIGO; UniProtKB:Q80ZD8}
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 229715, 295365, 57463
• Content And Storage: -20°C
• Form: Liquid