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Amlexanox, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
68302-57-8
C16H14N2O4
298.298
SGRYPYWGNKJSDL-UHFFFAOYSA-N
amlexanox,aphthasol,amoxanox,2-amino-7-isopropyl-5-oxo-5h-chromeno 2,3-b pyridine-3-carboxylic acid,amlenanox,solfa,amlexanoxo,amlexanoxum,amlexanoxum latin,amlexanoxo spanish
2161
CHEBI:31205
2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid
CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
This item is not returnable. View return policy
68302-57-8
C16H14N2O4
298.298
SGRYPYWGNKJSDL-UHFFFAOYSA-N
amlexanox,aphthasol,amoxanox,2-amino-7-isopropyl-5-oxo-5h-chromeno 2,3-b pyridine-3-carboxylic acid,amlenanox,solfa,amlexanoxo,amlexanoxum,amlexanoxum latin,amlexanoxo spanish
2161
CHEBI:31205
2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid
CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N

Selective inhibitor of TBK

Selective inhibitor of TANK-binding kinase 1 (TBK1) and IKKε (IC50 values are ∽1-2 μM). Displays no effect on IKKα or IKKβ at these concentrations. Reversibly lowers weight, increases insulin sensitivity, and reduces inflammation and steatosis in three mouse models of obesity. Exhibits antiallergic activity; inhibits the release of histamine from rat mast cells. Also binds to Hsp90 and inhibits C-terminal chaperone activity in vitro.
Quantity 10mg
Formula Weight 298.29
Percent Purity >99%
Chemical Name or Material Amlexanox

Recommended Storage : Store at -20°C